Current Job Postings

CURRENT CAREER OPPORTUNITIES

To learn more, please click VIEW DESCRIPTION for any of the positions listed below. To apply for a position, click on the title of the job posting.

There are: 7 Job Openings at Oncobiologics Inc.

View Description
Job Description:

 

Oncobiologics is pursuing a scientist with extensive industry experience to play an integral part ofour Phage Display platform to screen hits, and lead-optimization activities in the field of therapeutic scFv and antibodies.  We are looking for an exceptionally talented scientist with a track record of scFv/antibody discovery with a passion/drive for the growth and success of the company objections in treating patient’s medical needs.

The Scientist will be reporting to the Project Leaders of Discovery Sciences.

 

Qualification and Experience:

  • PhD/MS in Biotechnology/Chemical Engineering/Biological Sciences, plus 2-5 years of experience in biotechnology industry
  • Strong knowledge of scFv, antibody and biologic structure-activity relationships, stability and protein engineering/computer modeling
  • Experienced required in: phage panning including solution and cell based screening, Bioassays, ELISA, Octet/Biacore and Flow Cytometry /FACS
  • Working hands on experience in cell culture and cell based assays
  • Knowledge of molecular biology, with recombinant DNA manipulation, PCR, cloning, subcloning using novel technologies such as E-Gels and Clonewell Technology
  • Strong molecular understanding in the therapeutic areas: oncology, immuno-oncology,  and inflammatory diseases
  • Experience in multiple external partnerships in discovery development with academic/medical labs
  • Broad knowledge of pre-clinical in-vitro assays and in-vivo animal test models
  • Experience managing multiple simultaneous projects timelines with team members
  • Protein sciences and biological-assay development and analytical skills in an industrial pharmaceutical or biotechnology environment
  • Extremely strong interpersonal skills, demonstrated ability to work in a highly collaborative environment and ability to achieve results though team work.
  • Extremely strong written and oral communication and presentation skills

 

Job Responsibilities:

  • Design, analyze and interpret experiments and development long term experimental plans  
  • Implement high-throughput methods for production, purification, and screening of lead hits isolated from specific selections criteria
  • Present and report research progress in individual meetings and group meetings in a professional manner, prepare project reports and project experimental timelines.
  • Scientific activities involving: implementation/application of theoretical concepts, problem solving, and contingency planning
  • Experience with automated equipment and flexibility to learn and set up new equipment and novel technologies
  • Plan for the proof of concept cell based assays and animal studies with lead-optimization activities

  Other Requirements:

  • Support business development activities as required.
  • Support solutions for innovation and all issues on collaboration.
  • Must be an excellent team member willing to work collaboratively
  Location: Cranbury, New Jersey  (map)
View Description
Job Description:

 

Qualifications & Experience:   BS in Biochemistry/Biotechnology or related field.

Minimum of 5 years relevant experience in analytical sciences of protein biotherapeutics (mAbs, antibody fusion proteins, and other protein constructs).

Hands on experience with HPLC equipment (instrument and detectors), Microplate shakers/washers/readers, and/or Capillary Electrophoresis instrumentation is required. Experience with cGMP regulations preferred. Motivation to be part of a high performance, diverse, and efficient scientific team. Excellent spoken and written communication skills.

 

Job Responsibilities:

Assist the Analytical Development Group in the development and performance of characterization and process impurity assays (70%)

 

  • Provide support, through analytical testing, of process development activities
  • Possess the capability to develop analytical testing assays for the characterization of Oncobiologics constructs
  • Possess the capability to develop analytical testing assays for the quantitation/qualification of process manufacturing impurities.
  • Ability to troubleshoot and maintain the equipment utilized within the department.
  • Maintain equipment logbooks and electronic notebook entries
  • Focus on established and new-art science and technology to meet project needs for analytical sciences.
  • Ability to collaborate, work closely and support future QC and Process Development activities on scientific issues.
     

Support publication and patenting of scientific work (20%)

Collaborate with various vendors and discovery centres to develop innovative novel analytical methodologies. Develop methods for qualification of analytical methodologies. Setup multi-platforms to be used to access biologics degradation pathways, and comparability protocols

 

Culture (10%)

Support business development activities as required. Support solutions for innovation and collaboration. Develop customer relationships with peers.

  Location: Cranbury, New Jersey  (map)
View Description
Job Description:

 

Qualification and Experience:

BS/MS in Life Science, Engineering or equivalent. 0-4 years of experience; must have demonstrated ability to design and evaluate experiments; statistical design of experiments is a plus and be flexible in executing and responding to changes in scheduling, along with innovating solutions in a transparent team environment; must have strong focus on creativity and continuous improvement.

Job Responsibilities:

This position will initially report to the Head of Upstream Development with responsibilities including but not limited to:
 

A.   ProcessDevelopment{40%)

  • Plan and execute experiments performed to evaluate mammalian cell lines, culture media, feeding strategies and process conditions.
  • Take accountability for ongoing experiments, by daily monitoring, data trending, sample analysis, and thorough data analysis
  • Work in collaboration with Operations group to execute protocols, experimental plans, and crit-ical production batches.
  • Represent functional area in team meetings as required.
  • Author experimental plans, reports, and operating procedures
  • Maintain a current laboratory notebook with scientific rigor to meet project needs for process development.
  • Implement state of the art science and technology with respect to media development, cell line development, primary recovery, and bioreactor systems while exploiting miniaturization to the extent possible.
  • Collaborate with other function to deliver an efficient low cost solution to customers.
  • Develop effective mammalian scale-down capabilities and implement effective and scalable process control strategies.
  • Media design and optimization for mammalian cell culture
     

B. Equipment and Facilities {40%)

  • Participate in design and start-up of facility and process equipment. Partner with vendors to deliver state of the art technologies.
  • Innovate technologies that enable the miniaturization of development systems and increase the efficiency of process development
  • Develop efficient and innovative solutions to enable multi-host development and cGMP
  • facility design and operation.
  • Follow full GMP guidance and fulfill all Quality Assurance requirements where required.
  • Operate safely and according to company environmental requirements.
     

    C. Culture (20%)

  • Evaluate technologies and propose ideas for innovation.
  • Support business development activities as required.
  • Present data or ideas in team meetings.
  • Follow all company best practices to minimize cost and meet budgetary requirements.
  • Head of Upstream Development may assign other responsibilities as required.
     

 

View Description
Job Description:

Qualification and Experience:

PhD/MS/BS in Life Science, Chemical Engineering or equivalent

Minimum 5+ years of experience in absence of graduate degree, 2+ years if MS, or entry level PhD; must have demonstrated ability to design and evaluate experiments; must utilize statistical design of experiments and be flexible in executing and responding to changes in scheduling, along with innovating solutions in a transparent team environment; must have strong focus on creativity and continuous improvement.

Job Responsibilities:

This position will report to the Head of Upstream Development with responsibilities including but not limited to:

Process Development (50%)

  • Plan and execute experiments performed to evaluate cell lines, culture media, feeding strategies and process conditions.
  • Work in collaboration with Operations group to execute protocols, experimental plans, critical production batches, and tech transfers.
  • Use designed experiments (DOE) to predict/understand/control the impact of process parameters on product quality (CQAs).
  • Represent functional area in team meetings as required.
  • Author experimental plans, reports, and operating procedures
  • Maintain a current laboratory notebook with scientific rigor to meet project needs for process development.
  • Implement state of the art science and technology with respect to media development, cell line development, primary recovery, and bioreactor systems while exploiting miniaturization to the fullest extent possible.
  • Collaborate with other function to deliver an efficient low cost solution to customers.
  • Support the transfer of processes to scale up/manufacturing sites.
  • Deliver desired performance using a range of industrially relevant feedstock’s and media components at lab and pilot scales (2 L - 2,000 L).
  • Work closely with the cell line development team to guide efforts toward scalable and robust culture processes.
  • Characterize and optimize processes, from a commercial scale perspective, through process development at lab and pilot scales to achieve established performance metrics and production cost targets for all products under development.
  • Develop effective mammalian scale-down capabilities and implement effective and scalable process control strategies.
  • Write technical reports, help developing SOPs and make oral presentations to summarize the results and investigations.
  • Follow standard operating procedures for laboratory duties, experiment design, data analysis and process monitoring
  • This position requires a desire and ability to work as an integral part of a multidisciplinary team, as well as the demonstration of a high degree of flexibility, creativity, and initiative applied to the various duties and aspects of the position

Equipment and Facilities (30%):

  • Participate in design and procurement of process equipment.  Partner with vendors to deliver state of the art technologies.
  • Innovate technologies that enable the miniaturization of development systems and increase the efficiency  of process development
  • Develop efficient and innovative solutions to enable cGMP facility design and operation.
  • Follow full GMP guidance and fulfill all Quality Assurance requirements where required.
  • Operate safely and according to company environmental requirements.

Culture (20%):

  • Evaluate technologies and propose ideas for innovation.
  • Support business development activities as required.
  • Present data or ideas in team meetings.
  • Follow all company best practices to minimize cost and meet budgetary requirements.
  • Head of Upstream Development may assign other responsibilities as required.
  • Provide mentoring, coaching, training to others.
  • Demonstrated technical leadership skills
  • Good oral and written communication skills
  • Must be able to work productively in an interdisciplinary team environment
  Location: Offisite: Cranbury, New Jersey  (map)
View Description
Job Description:

 

Oncobiologics is seeking a scientist with extensive industry experience to play an integral part and manage our Phage Display platform to screen hits, and lead-optimization activities in the field of therapeutic scFv and antibodies.  We are looking for an exceptionally talented scientist/leader with a track record of scFv/antibody discovery with a passion/drive for the growth and success of the company objections in treating patient’s medical needs.

Qualifications & Experience

  • PhD in Biotechnology/Chemical Engineering/Biological Sciences, plus 5-10 years of program-leadership experience in biotechnology industry
  • Strong knowledge of scFv, antibody and biologic structure-activity relationships, stability and protein engineering/computer modeling
  • Experienced in phage panning including solution and cell based screening, Bioassays, ELISA, Octet/Biacore and Flow Cytometry /FACS
  • Knowledge of molecular biology, with recombinant DNA manipulation, PCR, cloning, subcloning using novel technologies such as E-Gels and Clonewell Technology
  • Strong molecular understanding in the therapeutic areas: oncology, immuno-oncology,  and inflammatory diseases
  • Experience in multiple external partnerships in discovery development with academic/medical labs
  • Broad knowledge of pre-clinical in-vitro assays and in-vivo

 

JOB RESPONSIBILITIES

This position will report to the Vice-President of Discovery and Development Sciences with responsibilities including (but not limited to):

  • Oversee and lead/manage a portfolio of discovery biologics programs and the Discovery scientists including  PhD’s.
  • Design, analyze and interpret experiments and development long term experimental plans  
  • Implement high-throughput methods for production, purification, and screening of lead hits isolated from specific selections criteria
  • Present and report research progress in individual meetings and group meetings in a professional manner, prepare project reports and project experimental timelines.
  • Critical-path management of scientific activities,  problem solving, and contingency planning
  • Experience with automated equipment and flexibility to learn and set up new equipment and novel technologies
  • Extensive experience with managing PhD level, MS level and BS level Scientists, ready to teach lab skills and explain theoretical concepts in a simplified manner to all level of Scientists
  • Plan for the proof of concept animal studies with lead-optimization activities

Support Company Culture

  • Support business development activities as required.
  • Support solutions for innovation and all issues on collaboration.
  • Must be an excellent team member willing to work collaboratively
View Description
Job Description:

 

Qualifications & Experience:

BS/MS/PhD in Biochemistry/Biotechnology/Analytical Chemistry or related subject area.

Minimum 5 - 6 years of relevant industry experience with focus on analytical quality control and analysis testing support for raw material release, drug substance/drug product lot release and stability for Biological Manufacture Center, Oncobiologics. The QC Senior Scientist will be responsible for QC lab operation management,QC method/data management and provides supports to QC head to meet project timelines in a fast-paced team environment

 

 

Job Description

This position will directly report to the Head of Quality Control with the general responsibilities including but not limited to:

Analytical Support for Biological Manufacture Center

 

  • Effectively interact with BMC and CRO for raw material release. Review and approve analytical test method/specification/results of raw material tested either in-house or by CRO in accordance with cGMP regulations. Ensure CROs are following analytical procedures and specifications.
  • Oversee sample submission tracking and document tracking used to the Quality Control laboratory specifying tests required for lot release, stability and cleaning validation.
  • Review of test results of drug substance, finished products, stability and microbiology samples using in-house and EP/USP methods for lot release and stability evaluation.
  • Update and track stability testing database as samples are tested and reviewed.
  • Coordinate the change control and planned deviations requests applicable to stability, lot release and raw material sample.
  • Review SOP’s, analytical procedures and product specifications to ensure that all standards are met in accordance with cGMP and company guidelines/FDA and EMA regulations.
  • Communicate review findings to QA/QP, discuss various approaches recommend solutions to audit findings and suggest appropriate CAPAs
  • Maintain and control laboratory documentation within QC.
  • Provide training to juror scientist. Responsible for QC lab safety.

Desired Key Competencies

  • Ability to understand and execute on the company’s mission and values.
  • Maintain a high degree of accuracy and attention to detail.
  • Well organized and capable of clear communication.

Culture

  • Foster a strong cross departmental team/interactive culture.
  • Support business development and strategic activities as required.
  • Support solutions for new innovation and collaboration with peers.
  • Follow all company best practices to minimize cost and meet budgetary requirements while maintaining quality.
  Location: Cranbury, New Jersey  (map)
View Description
Job Description:

Qualifications:

  • Ph.D./MS or BS in biology, cell biology, biochemistry or related field.
  • With a M.S. a minimum of 6 years of experience in cell culture and developing cell based bioassays and/or immunoassays for the purpose of monitoring selective product quality attributes required. With a B.S. a minimum of 9 years of relevant experience in cell culture and developing cell based bioassays and/or immunoassays for the purpose of monitoring selective product quality attributes required.
  • Proven track record of providing scientifically sound results while multitasking in a fast paced environment.
  • Effective communicator in a team oriented group based environment.
  • Experience in both research based and GxP environments.

Experience:  

Development, testing, and maintenance of assays that evaluate cell based functional potency in release, stability, and process development test articles. A thorough understanding of cell culture techniques is required. Experience in assay development aimed at determining test article structure/function attributes. Experience in assay development and testing of SPR based assays (Biacore, Octet) is desired.

Job Responsibilities:

Assist the Analytical Development Group in the development and performance of characterization and process impurity assays (70%)

  • Provide support, through analytical testing, of process development activities
  • Possess the capability to develop analytical testing assays for the characterization of test article product quality attributes
  • Possess the capability to adequately maintain, through properly established cell culture techniques,  project related cell lines.
  • Ability to troubleshoot and maintain the equipment utilized within the department.
  • Maintain equipment logbooks and electronic notebook entries
  • Focus on established and new-art science and technology to meet project needs for analytical sciences.
  • Ability to collaborate, work closely and support future QC and Process Development activities on scientific issues.

Support publication and patenting of scientific work (20%)

Collaborate with various vendors and discovery centres to develop innovative novel analytical methodologies. Develop methods for qualification of analytical methodologies. Setup multi-platforms to be used to access biologics degradation pathways, and comparability protocols.

Culture (10%)

Support business development activities as required. Support solutions for innovation and collaboration. Develop customer relationships with peers.

 

 

 

  Location: Cranbury, NJ  (map)