Current Job Postings

CURRENT CAREER OPPORTUNITIES

To learn more, please click VIEW DESCRIPTION for any of the positions listed below. To apply for a position, click on the title of the job posting.

There are: 8 Job Openings at Oncobiologics Inc.

View Description
Job Description:

 

Oncobiologics is pursuing a scientist with extensive industry experience to play an integral part ofour Phage Display platform to screen hits, and lead-optimization activities in the field of therapeutic scFv and antibodies.  We are looking for an exceptionally talented scientist with a track record of scFv/antibody discovery with a passion/drive for the growth and success of the company objections in treating patient’s medical needs.

The Scientist will be reporting to the Project Leaders of Discovery Sciences.

 

Qualification and Experience:

  • PhD/MS in Biotechnology/Chemical Engineering/Biological Sciences, plus 2-5 years of experience in biotechnology industry
  • Strong knowledge of scFv, antibody and biologic structure-activity relationships, stability and protein engineering/computer modeling
  • Experienced required in: phage panning including solution and cell based screening, Bioassays, ELISA, Octet/Biacore and Flow Cytometry /FACS
  • Working hands on experience in cell culture and cell based assays
  • Knowledge of molecular biology, with recombinant DNA manipulation, PCR, cloning, subcloning using novel technologies such as E-Gels and Clonewell Technology
  • Strong molecular understanding in the therapeutic areas: oncology, immuno-oncology,  and inflammatory diseases
  • Experience in multiple external partnerships in discovery development with academic/medical labs
  • Broad knowledge of pre-clinical in-vitro assays and in-vivo animal test models
  • Experience managing multiple simultaneous projects timelines with team members
  • Protein sciences and biological-assay development and analytical skills in an industrial pharmaceutical or biotechnology environment
  • Extremely strong interpersonal skills, demonstrated ability to work in a highly collaborative environment and ability to achieve results though team work.
  • Extremely strong written and oral communication and presentation skills

 

Job Responsibilities:

  • Design, analyze and interpret experiments and development long term experimental plans  
  • Implement high-throughput methods for production, purification, and screening of lead hits isolated from specific selections criteria
  • Present and report research progress in individual meetings and group meetings in a professional manner, prepare project reports and project experimental timelines.
  • Scientific activities involving: implementation/application of theoretical concepts, problem solving, and contingency planning
  • Experience with automated equipment and flexibility to learn and set up new equipment and novel technologies
  • Plan for the proof of concept cell based assays and animal studies with lead-optimization activities

  Other Requirements:

  • Support business development activities as required.
  • Support solutions for innovation and all issues on collaboration.
  • Must be an excellent team member willing to work collaboratively
  Location: Cranbury, New Jersey  (map)
View Description
Job Description:

 

Oncobiologics is seeking a scientist with extensive industry experience to play an integral part and manage our Phage platform to screen hits and lead-optimization activities in the field of therapeutic scFv and antibodies. We are looking for an exceptionally talented scientist/leader with a track record of scFv/antibody discovery with a passion/drive for the growth and success of the company objectives in treating patient’s medical needs.

The Director will report to the Vice President of Discovery and Development Sciences.
 

Qualification and Experience:

  • PhD in a field of biological/ protein sciences, plus 15 years of program-leadership experience in biotechnology industry
  • Strong knowledge of scFv, antibody and biologic structure-activity relationships and protein engineering/computer modeling
  • Experienced in PHAGE screening, and bio assays, ELISA, Octet and flow cytometry/FACS
  • Knowledge of molecular biology, with recombinant DNA manipulation, PCR, cloning, subcloning
  • Strong molecular understanding in the therapeutic areas: oncology, immuno-oncology,  and inflammatory diseases
  • Experience in multiple external partnerships in discovery development with academic/medical labs
  • Broad knowledge of pre-clinical in-vitro assays and in-vivo animal test models
  • Experience managing a lab and proven ability to oversee multiple simultaneous projects timelines with lab personnel
  • Strong management skill in assisting the development of lab personnel  and to engaged their motivation/passion to succeed
  • protein sciences and biological-assay development and analytical skills in an industrial pharmaceutical or biotechnology environment
  • Extremely strong interpersonal skills, demonstrated ability to work in a highly collaborative environment and ability to achieve results though team work.
  • Extremely strong written and oral communication and presentation skills
     

Job Responsibilities:

  • Oversee and lead/manage a portfolio of discovery biologics programs and the Discovery team of 8 scientists including PhD’s.
  • Work with teams leaders to develop and maintain timelines and resource plans
  • Design, analyze and interpret experiments and development long term experimental plans  
  • Implement high-throughput methods for production, purification, and screening of lead hits isolated from specific selections criteria’s
  • Obtain input from all group leader and external collaborators/scientific advisory broad members on project goals and data.
  • Plan for the POC animal studies with lead-optimization activities
  • Critical-path management of scientific activities,  problem solving, and contingency planning
  • Required to work in the laboratory with the team
     

  Culture

  • Support business development activities as required.
  • Support solutions for innovation and all issues on collaboration.
  • Must be an excellent team member willing to work collaboratively
     
  Location: Cranbury, New Jersey  (map)
View Description
Job Description:

 

Qualifications & Experience:   BS in Biochemistry/Biotechnology or related field.

Minimum of 5 years relevant experience in analytical sciences of protein biotherapeutics (mAbs, antibody fusion proteins, and other protein constructs).

Hands on experience with HPLC equipment (instrument and detectors), Microplate shakers/washers/readers, and/or Capillary Electrophoresis instrumentation is required. Experience with cGMP regulations preferred. Motivation to be part of a high performance, diverse, and efficient scientific team. Excellent spoken and written communication skills.

 

Job Responsibilities:

Assist the Analytical Development Group in the development and performance of characterization and process impurity assays (70%)

 

  • Provide support, through analytical testing, of process development activities
  • Possess the capability to develop analytical testing assays for the characterization of Oncobiologics constructs
  • Possess the capability to develop analytical testing assays for the quantitation/qualification of process manufacturing impurities.
  • Ability to troubleshoot and maintain the equipment utilized within the department.
  • Maintain equipment logbooks and electronic notebook entries
  • Focus on established and new-art science and technology to meet project needs for analytical sciences.
  • Ability to collaborate, work closely and support future QC and Process Development activities on scientific issues.
     

Support publication and patenting of scientific work (20%)

Collaborate with various vendors and discovery centres to develop innovative novel analytical methodologies. Develop methods for qualification of analytical methodologies. Setup multi-platforms to be used to access biologics degradation pathways, and comparability protocols

 

Culture (10%)

Support business development activities as required. Support solutions for innovation and collaboration. Develop customer relationships with peers.

  Location: Cranbury, New Jersey  (map)
View Description
Job Description:

Qualification and Experience:

BS/MS degree with a minimum of 10 years or a PHD degree with 5 years hands-on experience in antibody/protein analyses with various liquid chromatography, liquid chromatography-mass spectrometry methods and biophysical characterization. The Senior Scientist must have strong interpersonal skills and the desire to work in a high pace biotech environment

Job Responsibilities:

This position will directly report to the director of Analytical Sciences with responsibilities including but not limited to:

Analytical Support for Process Development, GMP Manufacture, Formulation and Drug Discovery

  • Effectively interact with Cell Line Development, Upstream, Downstream, Formulation and Drug Discovery to support biologics development.Ensure timely support.
  • Take a lead for conducting routine testing in support of antibody/protein glycosylation characterization (N-glycans, monosaccharaides, sialic acid), primary structure characterization (amino acid sequence coverage analysis, molecular weight determination, amino acid composition analysis, cysteine conformation, free thiol content) and post translational modifications characterization.
  • Responsible for method development of carbohydrates analysis, glycation, acidic/basic species of charge isoforms identification and mass spec new methods.
  • Responsible for assay qualification, validation and assay transfer/training.
  • Take a lead for troubleshooting of analytical issuers.
  • Provide training to juror scientists.
  • Maintain accurate and timely data records and documentation. Writes SOPs and updates and keeps them current.
  • Work with CRO for biophysical characterization.
  • Write publication of scientific work.

Desired Key Competencies

  • Ability to understand and execute on the company’s mission and values.
  • Provides supports to the grouplead to meet project timelines in a fast-paced team environment
  • Maintain a high degree of accuracy and attention to detail.
  • Well organized and capable of clear communication through technology.

Culture

  • Foster a strong cross departmental team interactive culture.
  • Support business development and strategies activities as required.
  • Support solutions for new innovation and collaboration with peersin company.
  • Follow all company best practices to minimize cost and meet budgetary requirements while
  • maintaining quality.
  Location: Offisite: Cranbury, New Jersey  (map)
View Description
Job Description:

 

Oncobiologics is seeking a scientist with extensive industry experience to play an integral part and manage our Phage Display platform to screen hits, and lead-optimization activities in the field of therapeutic scFv and antibodies.  We are looking for an exceptionally talented scientist/leader with a track record of scFv/antibody discovery with a passion/drive for the growth and success of the company objections in treating patient’s medical needs.

Qualifications & Experience

  • PhD in Biotechnology/Chemical Engineering/Biological Sciences, plus 5-10 years of program-leadership experience in biotechnology industry
  • Strong knowledge of scFv, antibody and biologic structure-activity relationships, stability and protein engineering/computer modeling
  • Experienced in phage panning including solution and cell based screening, Bioassays, ELISA, Octet/Biacore and Flow Cytometry /FACS
  • Knowledge of molecular biology, with recombinant DNA manipulation, PCR, cloning, subcloning using novel technologies such as E-Gels and Clonewell Technology
  • Strong molecular understanding in the therapeutic areas: oncology, immuno-oncology,  and inflammatory diseases
  • Experience in multiple external partnerships in discovery development with academic/medical labs
  • Broad knowledge of pre-clinical in-vitro assays and in-vivo

 

JOB RESPONSIBILITIES

This position will report to the Vice-President of Discovery and Development Sciences with responsibilities including (but not limited to):

  • Oversee and lead/manage a portfolio of discovery biologics programs and the Discovery scientists including  PhD’s.
  • Design, analyze and interpret experiments and development long term experimental plans  
  • Implement high-throughput methods for production, purification, and screening of lead hits isolated from specific selections criteria
  • Present and report research progress in individual meetings and group meetings in a professional manner, prepare project reports and project experimental timelines.
  • Critical-path management of scientific activities,  problem solving, and contingency planning
  • Experience with automated equipment and flexibility to learn and set up new equipment and novel technologies
  • Extensive experience with managing PhD level, MS level and BS level Scientists, ready to teach lab skills and explain theoretical concepts in a simplified manner to all level of Scientists
  • Plan for the proof of concept animal studies with lead-optimization activities

Support Company Culture

  • Support business development activities as required.
  • Support solutions for innovation and all issues on collaboration.
  • Must be an excellent team member willing to work collaboratively
View Description
Job Description:

 

Qualifications & Experience:

BS/MS/PhD in Biochemistry/Biotechnology/Analytical Chemistry or related subject area.

Minimum 5 - 6 years of relevant industry experience with focus on analytical quality control and analysis testing support for raw material release, drug substance/drug product lot release and stability for Biological Manufacture Center, Oncobiologics. The QC Senior Scientist will be responsible for QC lab operation management,QC method/data management and provides supports to QC head to meet project timelines in a fast-paced team environment

 

 

Job Description

This position will directly report to the Head of Quality Control with the general responsibilities including but not limited to:

Analytical Support for Biological Manufacture Center

 

  • Effectively interact with BMC and CRO for raw material release. Review and approve analytical test method/specification/results of raw material tested either in-house or by CRO in accordance with cGMP regulations. Ensure CROs are following analytical procedures and specifications.
  • Oversee sample submission tracking and document tracking used to the Quality Control laboratory specifying tests required for lot release, stability and cleaning validation.
  • Review of test results of drug substance, finished products, stability and microbiology samples using in-house and EP/USP methods for lot release and stability evaluation.
  • Update and track stability testing database as samples are tested and reviewed.
  • Coordinate the change control and planned deviations requests applicable to stability, lot release and raw material sample.
  • Review SOP’s, analytical procedures and product specifications to ensure that all standards are met in accordance with cGMP and company guidelines/FDA and EMA regulations.
  • Communicate review findings to QA/QP, discuss various approaches recommend solutions to audit findings and suggest appropriate CAPAs
  • Maintain and control laboratory documentation within QC.
  • Provide training to juror scientist. Responsible for QC lab safety.

Desired Key Competencies

  • Ability to understand and execute on the company’s mission and values.
  • Maintain a high degree of accuracy and attention to detail.
  • Well organized and capable of clear communication.

Culture

  • Foster a strong cross departmental team/interactive culture.
  • Support business development and strategic activities as required.
  • Support solutions for new innovation and collaboration with peers.
  • Follow all company best practices to minimize cost and meet budgetary requirements while maintaining quality.
  Location: Cranbury, New Jersey  (map)
View Description
Job Description:

Qualifications:

  • Ph.D./MS or BS in biology, cell biology, biochemistry or related field.
  • With a M.S. a minimum of 6 years of experience in cell culture and developing cell based bioassays and/or immunoassays for the purpose of monitoring selective product quality attributes required. With a B.S. a minimum of 9 years of relevant experience in cell culture and developing cell based bioassays and/or immunoassays for the purpose of monitoring selective product quality attributes required.
  • Proven track record of providing scientifically sound results while multitasking in a fast paced environment.
  • Effective communicator in a team oriented group based environment.
  • Experience in both research based and GxP environments.

Experience:  

Development, testing, and maintenance of assays that evaluate cell based functional potency in release, stability, and process development test articles. A thorough understanding of cell culture techniques is required. Experience in assay development aimed at determining test article structure/function attributes. Experience in assay development and testing of SPR based assays (Biacore, Octet) is desired.

Job Responsibilities:

Assist the Analytical Development Group in the development and performance of characterization and process impurity assays (70%)

  • Provide support, through analytical testing, of process development activities
  • Possess the capability to develop analytical testing assays for the characterization of test article product quality attributes
  • Possess the capability to adequately maintain, through properly established cell culture techniques,  project related cell lines.
  • Ability to troubleshoot and maintain the equipment utilized within the department.
  • Maintain equipment logbooks and electronic notebook entries
  • Focus on established and new-art science and technology to meet project needs for analytical sciences.
  • Ability to collaborate, work closely and support future QC and Process Development activities on scientific issues.

Support publication and patenting of scientific work (20%)

Collaborate with various vendors and discovery centres to develop innovative novel analytical methodologies. Develop methods for qualification of analytical methodologies. Setup multi-platforms to be used to access biologics degradation pathways, and comparability protocols.

Culture (10%)

Support business development activities as required. Support solutions for innovation and collaboration. Develop customer relationships with peers.

 

 

 

  Location: Cranbury, NJ  (map)
View Description
Job Description:

 

Qualification & Experience:

High school with technical school, apprenticeship program or equivalent experience.  Minimum of 10 years of experience with demonstrated knowledge and abilities in facility and equipment operation and maintenance.  The applicant should have the skills to troubleshoot and repair malfunctioning manufacturing and facilities equipment.  The applicant should have abilities in general facilities work including plumbing, carpentry, HVAC, and electrical work. Prior pharmaceutical experience preferred.

Job Description:

This position will work diligently to meet scheduled timelines, and will work overtime as required to support operations.  Weekend, holiday, off shift, and call in work may be required to maintain operations.  This position will report to the Manager of Facilities and Environment Health and Safety with responsibilities including (but not limited to):

Research & Development and cGMP Equipment Maintenance (40%)

  • Perform equipment inspections and preventative maintenance on cGMP facility, lab, and manufacturing equipment.
  • Coordinate and supervise contractors as needed for repairs, calibrations, preventative maintenance, and construction work.
  • Make necessary repairs to equipment as needed.
  • Maintain equipment calibration and maintenance history and records.

Research & Development and cGMP Facility Infrastructure (40%)

  • Maintain and repair facility systems and utilities including, but not limited to:  HVAC, electrical, plumbing, DI water system, steam system, Bio-hazardous waste removal, specialty gases, compressed air system, housekeeping, security system, environmental health and safety.
  • Make necessary repairs to the facilities as needed.
  • Coordinate and supervise sub-contractors for modifications, maintenance and repairs of the existing facilities.
  • Purchase parts and materials as needed, maintain supplies for facility and equipment.
  • Maintain security and fire systems.
  • Maintain facility maintenance history.
  • Operate and maintain forklift.

Culture (20%)

  • Work with Facility manager and all departments to deliver efficient low cost solutions for maintenance of facilities and equipment.
  • Follow full cGMP guidance and fulfill all regulatory requirements at all times.
  • Maintain all equipment and facilities in a safe and environmentally conscious manner.
  • Follow all company best practices to minimize cost and meet budgetary requirements.
  • Management may assign other responsibilities as required.
  Location: Cranbury, New Jersey  (map)